An iPSCs-based approach to model Type Two Diabetes in-vitro

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Project Description

Studying the transcriptional and epigenetic mechanisms dysregulated in patients affected by metabolic disorders such as insulin resistance (IR) and type 2 diabetes mellitus (T2DM) is essential to derive efficient pharmacological approaches. We are seeking an outstanding student to work on a project focused on the study of the role of histone modifiers to the onset of metabolic disorders.​​​​​​
Program - BioScience
Division - Biological and Environmental Sciences and Engineering
Faculty Lab Link - an-ipscs-based-approach-to-model-type-two-diabetes-in-vitro
Field of Study - ​Molecular and Cellular Biology and/or Bioinformatics

About the
Researcher

Antonio Adamo

Assistant Professor, Bioscience

Antonio Adamo

Desired Project Deliverables

​The selected candidate will use human stem cells and terminally differentiated glucose sensitive cell types and will acquire skills in molecular biology techniques including Chromatin Immuno-precipitation (ChIP), quantitative real-time PCR (Q-PCR) and next generation sequencing (NGS).​