Microscopy techniques based on vibrational spectroscopy are poised to be part of the next generation of microscopes for biological applications based on their unique chemical contrast and sub-cellular resolution for non-invasive, non-destructive and label free imaging of biological samples as live cells. The project will focus on the development of a fast and low-noise detection system in a setup for microscopic vibrational spectroscopy based on Stimulated Raman Scattering, which is one of the most advanced and sensitive methods for label-free microscopy for bio-imaging. The system will be applied to vibrational imaging of cancer stem cells to unveil their specific bio-chemical signatures. ​ ​​​​